Denny Solomona made his England debut a game to remember with a sensational late solo try, defeating Argentina 38-34 in an epic Test match.
A loose, entertaining contest full of running, it was Argentina who led at half-time thanks to tries from Emiliano Boffelli and Tomás Lavanini, plus a Nicolás Sánchez penalty, with Marland Yarde crossing for England as the score stood at 17-13.
George Ford's firing boot and a try from Jonny May put England ahead before the lead changed hands again in San Juan, two quick tries from Jerónimo de la Fuente and Joaquín Tuculet giving Argentina a 31-23 cushion with a pair of sensational finishes.
Ford tied things up with a penalty on try, building up to a tense conclusion, before Juan Martín Hernández slotted over a drop goal that looked to have to won an enthralling contest.
Up stepped Solomona, at fault for two of Argentina's tries, to race clear for a sensational solo score with two minutes left, winning the game as a result.
Sánchez's early attempt to open the scoring was unsuccessful, after Nathan Hughes was penalised at the scrum, with his effort from a long way out missing the posts.
Argentina started far better and were rightly rewarded through a try for Boffelli on debut, the hard carrying from the Argentine pack making the space down the blindside. The grubber from Sánchez was spot on, with Boffelli winning the race and rightly celebrating with plenty of enthusiasm.
England needed to settle, a youthful team showing their nerves, and after Lucas Noguera Paz was penalised around the breakdown Ford stepped up to make it 7-3.
As time wore on however England's confidence grew, winning penalties at the scrum and ruck, with Ford stepping up for his second penalty to cut the gap to a point.
Much was made of England's lighter backline but the resulting speed and skill was on full display for England's opening try, all starting from Alex Lozowski's break.
England stayed calm, recycling the ball through offloads before getting it wide where Yarde had the easy task or rounding prop Enrique Pieretto. Ford's conversion made the score 13-7.
The visitors' enthuiasm then proved costly, Ellis Genge sticking out a hand for a pass and knocking in the process as Argentina pounced through Jerónimo de la Fuente. Lavanini capitalised, the big lock powering his way over the line as Argentina hit back. With the conversion from Sánchez, Argentina led again, in a contest that whilst littered with turnovers certainly had the crowd entertained.
Argentina had the final say of the half, winning a penalty from the maul which Sánchez knocked over to move past 500 points for his country, joining the great Hugo Porta and Felipe Dominguez as the only players to pass that landmark, as los Pumas led 17-13.
England started the second half with Ford closing the gap thanks to his third penalty, after another ruck offence from Argentina, and they might have had more if Marland Yarde's break had been capitalised on shortly after.
Turns out the score wasn't far off, a brilliant step and grubber kick from Henry Slade finished off by May, with Brown not far behind him. Ford converted from the touchline, making the score 17-23.
Argentina then hit back from a set-piece, Denny Solomona on debut slipping as Martín Landajo raced clear, feeding De la Fuente for the try. Sánchez made no mistake with the conversion, switching the lead once more.
The best was still to come, Argentina with their tails up scoring an outsanding try starting deep in their 22, Solomona again at fault with a missed tackle as Matías Orlando and Matías Moroni combined to release Tuculet for try number four, and a 31-23 lead.
Eager to extend the lead Sánchez attemped a drop goal, his attempt falling way wide, but the Argentine scrum impressed with a pushover penalty. Sánchez couldn't convert, the gap staying at eight points.
England soon closed in, Ford adding a penalty before scoring a breakout try of his own, Piers Francis off he bench on debut with a quality offload. For once Ford missed off the tee, tying the scores at 31-31 to set up a grandstand finish.
Hernández stepped up for the drop goal, leaving Argentina three minutes to hang on for the win. They couldn't do so, Francis releasing the fleet-footed Solomona, who brushed off a tackle before outpacing Moroni to race clear for the winning try. It was a fitting end to a spectacular contest.
The scorers:
For Argentina:
Tries: Boffelli, Lavanini, De la Fuente, Tuculet
Cons: Sánchez 3
Pen: Sánchez
Drop Goal: Hernández
For England:
Tries: Yarde, May, Ford, Solomona
Cons: Ford 3
Pens: Ford 4
Argentina: 15 Joaquín Tuculet, 14 Matías Moroni, 13 Matías Orlando, 12 Jerónimo de la Fuente, 11 Emiliano Boffelli, 10 Nicolás Sánchez, 9 Martín Landajo, 8 Juan Manuel Leguizamón, 7 Javier Ortega Desio, 6 Pablo Matera, 5 Tomás Lavanini, 4 Matías Alemanno, 3 Enrique Pieretto, 2 Agustín Creevy, 1 Lucas Noguera Paz
Replacements: 16 Julián Montoya, 17 Santiago García Botta, 18 Nahuel Tetaz Chaparro, 19 Guido Petti, 20 Leonardo Senatore, 21 Gonzalo Bertanou, 22 Juan Martín Hernández, 23 Ramiro Moyano
England: 15 Mike Brown, 14 Marland Yarde, 13 Henry Slade, 12 Alex Lozowski, 11 Jonny May, 10 George Ford, 9 Danny Care, 8 Nathan Hughes, 7 Tom Curry, 6 Mark Wilson, 5 Charlie Ewels, 4 Joe Launchbury, 3 Harry Williams, 2 Dylan Hartley (c), 1 Ellis Genge
Replacements: 16 Jack Singleton, 17 Matt Mullan, 18 Will Collier, 19 Nick Isiekwe, 20 Don Armand, 21 Jack Maunder, 22 Piers Francis, 23 Denny Solomona
Referee: Nigel Owens (Wales)
Assistant Referees: John Lacey (Ireland), Egon Seconds (South Africa)
TMO: Aaron Paterson (New Zealand)
Tries from Ali Price, Tim Visser, Damien Hoyland and a brace from Ross Ford proved too much for Italy, who scored through tries from Michele Campagnaro and Angelo Esposito.
Tries from Akihito Yamada, Kenki Fukuoka and Michael Leitch saw them to the success, with Jumpei Ogura kicking 18 points from the tee.
Tries from Israel Folau (2), Henry Speight (2) and Stephen Moore saw them to victory, with Bernard Foley kicking 12 points in a slick showing.
Only one try was scored in the game and it went the way of Irish lock Iain Henderson, as the hosts held on for a morale-boosting success.
A 20-minute spell on the Welsh line was the conclusion to this fixture as Camille Chat's try, converted by Camille Lopez, saw France win.
The home side were full value for their win as they dominated for large periods — especially during the first half — although Italy will be disappointed with their effort and poor goalkicking from Carlo Canna, who failed to convert three penalties in the first half, meant they failed to score any points.
A hat-trick from outside centre Jonathan Joseph led the way for Eddie Jones' charges, with Anthony Watson, Billy Vunipola and Danny Care (2) also crossing as they move an impressive eight points clear in the table.
Italy took a surprise lead through Sergio Parisse but France responded in kind through Gaël Fickou, with three penalties from Camille Lopez to two from Carlo Canna giving France a 16-11 advantage by the break.
North's try and a Leigh Halfpenny penalty handed Wales an 8-6 half-time advantage, after three-pointers in response from Johnny Sexton and Paddy Jackson.
Eddie Jones's men stuttered and fumbled their way through the first half allowing Italy's intensity to throw them off their game after Giovanbattista Venditti scored just before halftime it looked as though Italy were about to claim their second big scalp under Conor O'Shea after beating South Africa in November.
Both teams were unaffected by Dublin's rainfall and produced a passionate game of rugby that typified European rivalry.
They had waited a decade for a victory over Wales, their last success coming at Murrayfield with a 21-9 win back in 2007, and ultimately were more than worthy victors after tries from Tommy Seymour and Tim Visser, remarkably winning the second half alone 20-0.
In an entertaining encounter, in which both teams kept the ball alive at every opportunity, momentum between the two sides ebbed and flowed, but it was the hosts who got the rub of the green in the end coming away with a deserved victory.
In an attritional encounter, in which both sides went at each other hammer and tongs for the full 80 minutes, Wales will be kicking themselves for losing this Test as they dominated for large periods.
Bouncing back from a first round loss to Scotland, the Irish were superb against the Azzurri as they made it six points from two matches.
Despite falling behind to Edoardo Gori's try on 29 minutes, Rob Howley's men hit back through Jonathan Davies, Liam Williams and George North with Leigh Halfpenny contributing 16 points from the tee in an assured display.
Although their campaign started with a win — and they have now stretched their winning run to 15 successive Tests — the defending champions' boss, Eddie Jones, will not be happy with his side's effort as they had to dig deep to win this one.